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Metformin is used when diet and exercise to prevent diabetes in people who are overweight. Metformin belongs to the class of drugs known as biguanides. Metformin reduces the amount of glucose in your blood. Metformin is used as a first line treatment of type 2 diabetes the pancreas does not produce sufficient insulin and the cells of the body are resistant to the low levels of insulin circulating in the blood. Metformin comes as a tablet and an extended-release tablet to take by mouth.